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Awareness regarding COVID-19 among health workers at Kastamonu education and research hospital

Aim: The knowledge of health care professionals about COVID- 19 disease increases day by day. No definitive medical treatment or vaccine is available to date. Health professionals all over the world now show a great example of virtue. The purpose of our questionnaire is to evaluate the awareness of the doctor, nurse and technical team working at the Kastamonu Education and Research Hospital about Covid -19 disease.

Material and Method: An online questionnaire was applied to 182 people working in Kastamonu Education and Research Hospital.  Our survey was divided into two sections: one-part consisted of 4 questions examining the participant characteristics, and the second part consisted of 11 questions examining COVID -19 disease awareness. While examining awareness of COVID-19 disease, the participants’ information sources, ways of transmission of the disease, symptoms, diagnostic methods, isolation time, risks, vaccines, drugs and prevention pathways were used in responses to general information questions. 

Results: Doctors, nurses and technical staff responded in a similar way to the awareness survey questions regarding general information about COVID-19 disease. We conclude that the most effective sources of learning about COVID-19 disease for the participants are social media and government guides.

Discussion: COVID-19 is a disease that is still unknown in the world, but health workers are learning about this disease from their own experience and reviews. As a result of our survey, we can say that healthcare professionals are wondering and learning about this disease.

 

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A Treatment arising from tradition: A Report of indigo blue therapy for granulomatous mastitis

The indigo plant is used globally for its blue dye, and plant-based indigo dyeing has been traditionally practiced for centuries in a broad geographic area. In addition to this purpose, indigo is used medically in many African tribal areas for its anti-inflammatory and anti-microbial effects. This article presents a case of granulomatous mastitis that was treated by a tribal healer with indigo blue, which provided temporary relief of symptoms for one year until secondary bacterial infection occurred. Some studies reported that indigo blue provides symptomatic relief related to its anti-oxidant, anti-microbial and anti-inflammatory mechanisms, which could be helpful in autoimmune diseases such as granulomatous mastitis. We strongly believe that this patient’s results warrant further investigation of indigo blue’s effect on granulomatous mastitis. 

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The relationship between Matrix Metalloproteinase-1 gene promoter (-1607) polymorphism and aggressive periodontitis

Aim: The purpose of this study was to investigate the role of Matrix metalloproteinase-1 (MMP-1) -1607 1G/2G promoter polymorphism in aggressive periodontitis (AgP).

Material and Methods: One hundred sixty-five systemically healthy volunteers comprising of 65 AgP and 100 periodontally healthy subjects were enrolled in this study. Full mouth radiological and clinical assessments of the periodontal tissues were performed. Genomic DNA was isolated from peripheral blood samples and amplified by PCR and analyzed by a restriction endonuclease.

Results: There was statistically no significant difference in genotype (p=0.79) and allele frequencies (p=0.99) of MMP-1 -1607 polymorphism between AgP patients and periodontally healthy control group. Additionally, multiple logistic regression analysis was performed to adjust for possible confounding factors, such as age gender and smoking.  Yet, the association still remained non-significant (p=0.57).  The odds ratio (OR) 1G/1G vs. 1G/2G+2G/2G was 0.75(0.28-2,0; p=0.57)

Discussion:  Early identification of individuals at high-risk of developing periodontal diseases might be helpful for prevention and may contribute to the treatment of disease. MMP-1 is biologically a promising candidate gene that is involved in pathogenesis of AgP.  However, our results showed that the MMP-1 (-1607) promoter polymorphism did not have a role in the susceptibility to AgP disease risk in Turkish population.

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